Recent developments
Muscle & Physical Function: What the Primary Evidence SupportsFunction beats mass. The muscle-longevity link is real but its load-bearing endpoint is strength and physical function, not muscle quantity. Grip…Stability trainingBalance and stability training sit at the bottom of most people's priority lists, somewhere below foam rolling and above nothing. That's a mistake with…Skeletal muscle (organ of longevity)Skeletal muscle does more than move you from place to place. It is an endocrine and metabolic organ that disposes of glucose, stores amino acids, and…Sarcopenia and muscle agingSarcopenia, the progressive loss of muscle mass and function with age, predicts how long you live more reliably than most lab tests your doctor orders.…Protein intakeThe RDA for protein, 0.8 g/kg of body weight per day, was derived from nitrogen-balance studies that most researchers now consider methodologically…Protein for muscle vs protein for longevity — the mTOR-IGF-1 tensionProtein builds muscle. Protein activates mTOR. mTOR inhibition extends life in mice. Follow that chain and you arrive at one of the sharpest tensions…Phosphocreatine systemCreatine's reputation rests on a specific piece of cell biology: the phosphocreatine system. Understanding how it works helps you separate the solid…Omega-3 and muscle health — disuse atrophy, anabolic sensitization, sarcopeniaOmega-3 fatty acids won't build muscle on their own. The evidence points to two specific contexts where EPA and DHA do something measurable: slowing…Creatine muscle — water weight vs hypertrophyCreatine's reputation for adding bulk has a well-earned asterisk: a chunk of that early weight gain is water, not muscle. A 2025 washout trial by Desai…Centenarian decathlonPeter Attia's centenarian decathlon starts with an unusual question: what do you want to be able to do physically at 88? Not "be healthy" in the…